According to a survey, 5 out of every 100 newborns have a spina bifida defect. As the name implies, spina bifida means that the dorsal spine and the surrounding spinal cord are not completely closed. Children with spina bifida may have leg and foot deformities, epilepsy and even lifelong paralysis. Recently, researchers at Leiden University and Erasmus Medical Center in the Netherlands are developing a new minimally invasive technique to correct fetal spina bifida. The new technology is said to use 3D printing technology to penetrate the uterus and begin to treat its spina bifida defects when the fetus is not born. The researchers said the technology will be put into use within a few years, and the study also received a €50,000 investment from the STW Technology Foundation.
Spinal fissures can generally be detected early in pregnancy by ultrasound. When this happens, prospective parents often face two choices: termination of pregnancy (legal) or surgery. If surgery is chosen, the doctor needs to open the mother's stomach and uterus to perform surgery on the fetus. However, whether it is for the mother or the fetus, this is a very risky operation. Even more tragic is that even surgery is a mere treatment and cannot be completely cured. Dick Oepkes, the first fetal treatment professor in the Netherlands, explained: "The toxic substances in the amniotic fluid have damaged the dorsal nerves of the fetus, so even if the surgeon sutures the defects on his back, it is only a treatment because the back nerves of the fetus have It was damaged before birth. It is said that the rest of these children will be spent in wheelchairs."
To replace the previous large-scale surgery, Oepkes and Alex Eggink at the Erasmus Center came up with another simple and safe early treatment. The combination of minimally invasive surgery and 3D printing technology, 3D printing a sealing ring and using a small needle directly into the uterus to close the spina bifida of the fetus. According to the researchers, this seal is very flexible and can grow with the fetus. Although this still does not completely cure the spina bifida, it can inhibit the damage of the back nerves and greatly improve the quality of life of these children in the future.
The latest €50,000 investment in this research comes from the Dutch Technology Foundation STW, which prepares a €101 million budget each year to help with technological innovation, mainly from the Dutch Scientific Research Organization (NOW), the National Education Culture and Ministry of Science, Department of Economic Affairs (EZ), and donations from private and business.
If the project goes well, pregnant women and fetuses with spina bifida are expected to use this new technology in the next few years. This is by far the first medical treatment to use 3D printing technology as a treatment for spina bifida.
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