**Product Name:** G418 Sulfate, Geneticin, Antibiotic G418
**Alternative Names:** G-418 Sulfate, Antibiotic G-418
**CAS Number:** 108321-42-2
**Molecular Formula:** Câ‚‚â‚€Hâ‚„â‚€Nâ‚„Oâ‚â‚€ · 2Hâ‚‚SOâ‚„
**Molecular Weight:** 692.71 g/mol
**Grade:** Biotech Grade
**Titer:** ≥600 U/mg
**Absorbance at A570 (100 mg/mL):** ≤0.1
**Absorbance at A280 (1 mg/mL):** ≤0.015
**Appearance:** White powder
**Description:** G418 is an aminoglycoside antibiotic that dissolves well in water and methanol. It is widely used in biochemical research for selecting both prokaryotic and eukaryotic cells that have been transfected with the neomycin resistance gene. This makes it a key tool in gene transfer studies, gene knockout experiments, and resistance screening. It is also commonly applied in the development of transgenic animals and cell lines.
**Storage:** Store at 2–8°C to maintain stability and potency.
G418 plays a critical role in molecular biology laboratories due to its effectiveness in identifying successfully transformed cells. Its ability to inhibit protein synthesis in susceptible cells ensures accurate selection during genetic engineering projects. Whether you're working on bacterial or mammalian systems, G418 provides a reliable and efficient method for screening resistant clones. Always handle with care and follow proper safety guidelines when using this reagent.
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